Does Transcranial Magnetic Stimulation Work in Depression?

Read latest publication on TMS in Depression published in JAMA Paychiatry by Yesavage and Colleagues

Transcranial Magnetic Stimulation in Depression

Question  Is repetitive transcranial magnetic stimulation an efficacious treatment for treatment-resistant major depression in patients who are veterans?

Findings  In this randomized clinical trial of 164 US veterans with depression, the overall remission rate was 39%, with no significant difference between the active and sham groups. Patients with comorbid posttraumatic stress disorder showed the least improvement.

Meaning  These findings may reflect the importance of close clinical surveillance, rigorous monitoring of concomitant medication, and regular interaction with clinic staff in bringing about significant improvement in this treatment-resistant population.